Prognostic indicators of Disseminated Intravascular Coagulation in pregnancy
نویسنده
چکیده
0bjective: The aim of this work is to evaluate the underlying causes, its complications, and effect of various DIC parameters on maternal outcomes. Method: This is prospective cum retrospective study.It included all Patients who developed DIC in pregnancy and postpartum in period of 2 years. Statistical analysis: Mean and percentage were used for presentation of the data. Result: The mean age of DIC patient is 27.35±3.11SD and mean of gestational age is 34±3.9week. This study show maximum no. of patients with PPH developed DIC. This may be the cause or consequences of DIC. Then next important cause is Preeclampsia, Septicemia, Acute fatty liver and IUD. DIC itself is a complication of various obstetrics condition but it also lead to various complications such as bleeding, renal dysfunction, liver dysfunction, respiratory dysfunction, shock, thromboembolic phenomenon and death. The diagnosis of DIC relies on clinical manifestations and laboratory tests. The diagnosis of DIC cannot made on a single laboratory value, but rather the constellation of laboratory markers and a consistent history of an illness known to cause DIC. FDP and D-Dimer are sensitive marker for diagnosis of DIC. From the present study it is concluded that DIC has high maternal (16%) mortality rate. Conclusion: Early diagnosis with prompt treatment, including a quick decision for surgical intervention, and eradication of predisposing conditions would minimize maternal morbidity and mortality. The treatment is urgent.
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